When their attempt to rob a casino owned by the feared gangster Pope goes awry and a shootout ensues, Vaughn and Cox are forced to flee on foot and hijack city Bus 657 and take the passengers hostage. Now, in a high speed chase, Vaughn will not only have to outwit the police, led by Officer Bajos who are in hot pursuit, but he will have to contend with Pope’s maniacal right hand man, Dog, in order to make it through the day alive.